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Characterization of Interactions between Heparin/Glycosaminoglycan and Adeno-Associated Virus with NANOSENSORS™ Super Sharp Silicon AFM probes

Divergent effect of glycosaminoglycans on the in vitro aggregation of serum amyloid A (http://dx.doi.org/10.1016/j.biochi.2014.05.007). Characterization of Interactions between eparin/Glycosaminoglycan and Adeno-Associated Virus (http://dx.doi.org/10.1021/bi4008676)

Check out the excellent work by Javier Aguilera and his coauthors. The authors used NANOSENSORS Super Sharp Silicon AFM tips to demonstrate awesome morphological features of AAV-2 and complexes with different heparin oligosaccharides and investigated the effect of glycosaminoglycans (GAGs) on the aggregation of serum amyloid A (SAA).

2014-09-18 09_06_46-20140826-142157-Characterization of Interactions between Heparin_Glycosaminoglyc

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视频介绍 – Uniqprobe原子力显微镜探针 – NANOSENSORS™

视频介绍 – Uniqprobe原子力显微镜探针 – NANOSENSORS™ 在 Youtube 和在 Youku http://v.youku.com/v_show/id_XNzA4MTgxNTI4.html?from=y1.7-1.2 NANOSENSORS公司的吴烨娴博士在本视频中介绍了Uniqprobe原子力显微镜探针。Uniqprobe 探针 的悬臂梁厚度均一,并且有局部的金反射涂层。这两个特点使得这个探针在一些对弹性系数有精确要求的应用中, 表现出卓越的机械性能一致性 。该探针特别适用于分子生物学,生物物理学和定量纳米机械的研究. Uniqprobe针尖的高度一般为7微米,针尖尖端的曲率半径通常小于10纳米。NANOSENSORS的uniqprobes有几种不同的悬臂类型。 其中接触和软接触型只有一个单独的矩形悬臂。这两种探针的弹性系数很低,可以在空气或液体中, 对软性生物材料进行接触模式测量。BioAC型号的Uniqprobe有着三条尺寸不同的悬臂,分别适用于空气和液体中 动态测量模式的各种应用。BioT型的uniqprobe有两个大小不同的三角形的悬臂,分别用于空气和液体中的测量。这两种悬臂都可用于接触模式和动态 模式的测量。

NANOSENSORS™ introduces new uniqprobe series – uniform quality SPM probes

SEM image of an uniqprobe cantilever.
SEM image of an uniqprobe cantilever.

SEM image of an uniqprobe cantilever.

The NANOSENSORS uniqprobe combines the well-known features of the other NANOSENSORS AFM probe series such as high application versatility and compatibility with most commercial SPMs with the additional advantage of a strongly reduced dispersion of force constant and resonance frequency.

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