Tag Archives: life sciences

Soft, drift-reduced AFM cantilevers for Biology and Life Sciences – Uniqprobe Screencast passes the 500 views mark

The screencast on the soft, drift-reduced NANOSENSORS uniqprobe cantilevers for biology and life science applications held by Dr. Laure Aeschimann has just passed the 500 views mark.
Congratulations Dr. Aeschimann!

This screencast is also available in Japanese:

and in Chinese:

The Chinese version is also available on Youku: http://v.youku.com/v_show/id_XNzA4MTgxNTI4.html
or weibo http://weibo.com/u/5077581192?is_all=1

 

バイオテクノロジー/ライフサイエンス向け NANOSENSORS ユニーク·プローブ Uniqprobe – for Biology and Life Science Applications – Japanese screencast

ユニーク·プローブはバイオテクノロジー/ライフサイエンス分野のAFMに最適なプローブです。クォーツのような材料を用い主に低バネ定数のプローブをラインアップしています。カンチレバーの厚さ精度が良く、プローブ間の機械的特性のばらつきが小さいのが特長です。さらに反射膜をカンチレバー背面の一部のみに限定することで液中測定でのドリフトを大幅に低減しています。他に類を見ない良さがあるユニーク·プローブを是非お使いください。

NANOSENSORS™ Uniqprobes®: Partially Coated Cantilever for Advances in Life Science AFM

Often it is necessary to add a coating to an AFM cantilever. In most cases it is a reflex coating on the backside of the cantilever to enhance the reflection of the laser to get a sufficient signal into the AFM photodetector.

Cantilever with partial coatings, varying from 20 to 100%.
NANOSENSORS™ cantilever with a reflex coating covering about 20, 40, 65 and 100% of the cantilever.

Unfortunately, adding a coating to a cantilever has several drawbacks such as:

  • a coating adds stress to the cantilever
  • when the cantilever is illuminated with the laser the so called Bimorph-Effect (if operating in liquids) will bend the cantilever and let the laser drift out of the photo-detector (thermal drift)
  • a higher damping of the cantilever which leads to a lower Q-factor
  • a higher noise of the cantilever

Those effects can be reduced dramatically when the coating is not done on the whole cantilever, but only on a part of it. The images above are showing cantilevers with a reflex coating covering about 20, 40, 65 and 100% of the cantilever.

To provide best quality with highest possible cantilever sensitivity NANOSENSORS™ manufactures their Uniqprobe® cantilever as the only AFM tip exclusively with a partial coating!

To learn more, please have a look at

the NANOSENSORS™ Uniqprobe® brochure