Tag Archives: life sciences

NANOSENSORS™ Uniqprobes®: Partially Coated Cantilever for Advances in Life Science AFM

Often it is necessary to add a coating to an AFM cantilever. In most cases it is a reflex coating on the backside of the cantilever to enhance the reflection of the laser to get a sufficient signal into the AFM photodetector.

Cantilever with partial coatings, varying from 20 to 100%.
NANOSENSORS™ cantilever with a reflex coating covering about 20, 40, 65 and 100% of the cantilever.

Unfortunately, adding a coating to a cantilever has several drawbacks such as:

  • a coating adds stress to the cantilever
  • when the cantilever is illuminated with the laser the so called Bimorph-Effect (if operating in liquids) will bend the cantilever and let the laser drift out of the photo-detector (thermal drift)
  • a higher damping of the cantilever which leads to a lower Q-factor
  • a higher noise of the cantilever

Those effects can be reduced dramatically when the coating is not done on the whole cantilever, but only on a part of it. The images above are showing cantilevers with a reflex coating covering about 20, 40, 65 and 100% of the cantilever.

To provide best quality with highest possible cantilever sensitivity NANOSENSORS™ manufactures their Uniqprobe® cantilever as the only AFM tip exclusively with a partial coating!

To learn more, please have a look at

the NANOSENSORS™ Uniqprobe® brochure

Spike up a Silicon Nitride AFM tip for high topography biology and life science imaging

Standard SiN AFM probes may have a lot of advantages for using them in your liquid cell measurements. But they also have their limits when it comes to high topographies on cells or other bio samples due to their relatively wide opening angle and the small 3µm tip height.

By teaming up with nanotools in Germany NANOSENSORS is able to offer you a “spiked-up” AFM tip – a silicon nitride probe with a long (10 µm) spike made of high density carbon grown on top of it – called Biotool XXL.

Customized versions such as other tip lengths or other cantilevers are also possible.

For more information please have a look at the NANOSENSORS special developments list or contact us at info@nanosensors.com

Biotool XXL AFM tip for high topography AFM imaging in biology
Biotool_XXL_AFM_tip

Visit our distributor NanoAndMore USA at booth no. 469 at Biophys

Learn more about the NANOSENSORS uniqprobes for biology and life science applications at the NanoAndMore booth no. 469 at the Biophysics Meeting in Baltimore this week. #bps15

NANOSENSORS uniqprobe - reduced thermal drift for biology and life-science applications
NANOSENSORS uniqprobe – reduced thermal drift for biology and life-science applications