Scanning Probe Microscopy

Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability

by NANOSENSORS
3 February 202115 March 2023
Science & Technology

Figure 4 from “Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability” by Cyriel Sebastiaan Olie et al. Disrupted cytoskeletal spatial organization in shPAB human muscle cell cultures. A Representative images of control and shPAB human muscle cell cultures, stained with antibodies to tubulin and actin, and the actin filaments were visualized with actin-GFP. B Tubulin staining in control and shPAB myoblast cell cultures after DMSO, 100 nM nocodazole or 25 nM paclitaxel treatment for 2 h. Scale bar is 25 µm. C Measurements of cell-mechanics properties in control and shPAB cells using the Brillouin Light Scattering Microscopy (Ci) or the Atomic Force Microscopy (Cii). Measurements were carried out in myoblasts; every dot represents the median from 1000 measurements in a cell. Cell stiffness is measured by GHz, and the young modulus reports the cell surface tension. Averages and standard deviations are from N = 15 cells. Statistical significance was calculated with the student’s t-test. NANOSENSORS uniqprobe qp-BioAC ( CB3 ) AFM probes were used in the quantitative imaging of cell-mechanics properties where a force curve is applied at each point.

Muscle wasting is connected with changes in various cellular mechanisms that influence protein homeostasis, transcription, protein acetylation and different metabolic pathways. * Scientific studies have… Read More »Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability

In‐situ force measurement during nano‐indentation combined with Laue microdiffraction

by NANOSENSORS
22 January 202115 March 2023
Science & Technology

image of a tuning fork based NANOSENSORS self-sensing and self-actuating Akiyama-probe (A-probe)

A NANOSENSORS™ self-sensing self-activating Akiyama probe was used in a home-built Scanning Probe Microscope for this interesting research article. *Florian Lauraux, Sarah Yehya, Stéphane Labat,… Read More »In‐situ force measurement during nano‐indentation combined with Laue microdiffraction

Nanoscale Charge Accumulation and Its Effect on Carrier Dynamics in Tri-cation Perovskite Structures

by NANOSENSORS
26 November 202015 March 2023
Science & Technology

Figure 3. from “Nanoscale Charge Accumulation and Its Effect on Carrier Dynamics in Tri-cation Perovskite Structures” by David Toth et al: Initial dark and relaxed closed-loop KPFM analysis of CsFAMAPbBrI. (a) Topography channel plotting surface height. (b) KPFM image prior to light pulse plotting Vcpd. (c) KPFM image seconds after the light pulse plotting Vcpd. (d) 3D topography overlaid with the calculated ΔVcpd map. (e) Histograms of before and after Vcpd maps separated into grain and GB responses. The double arrows indicate the difference between the mean values of the distributions. NANOSENSORS™ Platinumum-Silicide PtSi-CONT AFM probes were used for the KPFM measurements.

Nanoscale investigations by scanning probe microscopy have provided major contributions to the rapid development of organic–inorganic halide perovskites (OIHP) as optoelectronic devices. Further improvement of… Read More »Nanoscale Charge Accumulation and Its Effect on Carrier Dynamics in Tri-cation Perovskite Structures

Multi-Channel Exploration of O Adatom on TiO2(110) Surface by Scanning Probe Microscopy

by NANOSENSORS
5 October 202015 March 2023
Science & Technology

Figure 5. from “Multiple images of TiO2(110) surface with atomic resolution and corresponding line profiles” by Huan Fei Wen et al. (a) Frequency shift (∆f) image, (b) tunneling current () image and (c) local contact potential difference (VLCPD) image. (d,e) The line profiles along the blue line on the surface in (b,c). (f0 = 805 kHz, Q = 27623, ∆f = −260 Hz, VDC = 1.3 V, VAC = 1.5 V, A = 500 pm, size: 3.5 × 3.2 nm2). Multiple images of TiO2(110) surface with atomic resolution and corresponding line profiles. (a) Frequency shift (∆f) image, (b) tunneling current () image and (c) local contact potential difference (VLCPD) image. (d,e) The line profiles along the blue line on the surface in (b,c). (f0 = 805 kHz, Q = 27623, ∆f = −260 Hz, VDC = 1.3 V, VAC = 1.5 V, A = 500 pm, size: 3.5 × 3.2 nm2). - Ultrastiff NANOSENSORS SD-T10L100 AFM probes were used.

In the article “Multi-Channel Exploration of O Adatom on TiO2(110) Surface by Scanning Probe Microscopy” Huan Fei Wen, Yasuhiro Sugawara and Yan Jun describe how… Read More »Multi-Channel Exploration of O Adatom on TiO2(110) Surface by Scanning Probe Microscopy

Macroscopic manifestation of domain-wall magnetism and magnetoelectric effect in a Néel-type skyrmion host

by NANOSENSORS
20 September 202015 March 2023
Science & Technology

Supplementary Figure 1 a – d from “Macroscopic manifestation of domain-wall magnetism and magnetoelectric effect in a Néel-type skyrmion host” by K. Geirhos et al: Typical ferroelectric do-main pattern observed on the (001) cleaved GaV4Se8 crystal surface atT=10 K. a, The topography is characterized by stripes roughly parallel to the [110] axis and folds parallel to the [010] axis. The latter originate in the differently oriented distortion of the ferroelastic domains. The color scale corresponds to the z-displacement of the tip. b ,In the dissipation channel of the nc-AFM every second domain appears bright. For the non-magnetic tip the dissipation originates from electric interactions. The dissipated power is indicated by the color scale. Please have a look at the full article to view the full supplementary figure. NANOSENSORS Platinum Silicide PtSi-FM AFM probes were used for the imaging.

In the article “Macroscopic manifestation of domain-wall magnetism and magnetoelectric effect in a Néel-type skyrmion host” Korbinian Geirhos, Boris Gross, Bertalan G. Szigeti, Andrea Mehlin,… Read More »Macroscopic manifestation of domain-wall magnetism and magnetoelectric effect in a Néel-type skyrmion host

Plant-Based Scaffolds Modify Cellular Response to Drug and Radiation Exposure Compared to Standard Cell Culture Models

by NANOSENSORS
7 September 202015 March 2023
Science & Technology

Plant-based scaffolds present many advantages over a variety of biomaterials.* Recent studies explored their potential to be repopulated with human cells and thus highlight a… Read More »Plant-Based Scaffolds Modify Cellular Response to Drug and Radiation Exposure Compared to Standard Cell Culture Models

Electric-field-driven non-volatile multi-state switching of individual skyrmions in a multiferroic heterostructure

by NANOSENSORS
24 August 202015 March 2023
Science & Technology

Figure 2 from “Electric-field-driven non-volatile multi-state switching of individual skyrmions in a multiferroic heterostructure” by Yadong Wang et al.: Electric-field-induced switching of individual skyrmion. The transferred average strain εave and corresponding magnetic domain evolution processes in the d ~ 350 nm a [Pt/Co/Ta]12 and b [Pt/Co/Ta]8 nano-dots in a cycle of E ranging from +10 to −10 kV cm−1. Positive εave (red dots) represents tensile strain while negative εave (blue dots) represents compressive strain. μ0H represents the external magnetic field except that from the MFM tip and here μ0H is equal to be 0 mT. The inset of b illustrates the spin texture of the magnetic domain that is encompassed by the red box. The stripe domain enclosed by the black box shows the initial state of the magnetic domain evolution path. The gray dots represent the corresponding electric field for the MFM images. The MFM contrast represents the MFM tip resonant frequency shift (Δf). The scale bar represents 250 nm. NANOSENSORS™ PPP-LM-MFMR low moment magnetic AFM probes were used

Electrical manipulation of skyrmions attracts considerable attention for its rich physics and promising applications. To date, such a manipulation is realized mainly via spin-polarized current… Read More »Electric-field-driven non-volatile multi-state switching of individual skyrmions in a multiferroic heterostructure

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