Liver fibrosis is characterized by excessive accumulation and remodeling of extracellular matrix (ECM) components, leading to altered tissue mechanics and progressive impairment of liver function.… Read More »Dynamics of Compartment-Specific Proteomic Landscapes of Hepatotoxic and Cholestatic Models of Liver Fibrosis
Mechanical forces are key regulators of cellular behavior and function, affecting many fundamental biological processes such as cell migration, embryogenesis, immunological responses, and pathological states.… Read More »Deformable microlaser force sensing
Morphogenesis requires embryonic cells to generate forces and perform mechanical work to shape their tissues. Incorrect functioning of these force fields can lead to congenital… Read More »Quantifying mechanical forces during vertebrate morphogenesis
Genetic and environmental factors are key drivers regulating organismal lifespan but how these impact healthspan is less well understood. Techniques capturing biomechanical properties of tissues… Read More »Mechanical properties measured by atomic force microscopy define health biomarkers in ageing C. Elegans
The mechanical properties and structural organization of membranes determine the functional state of red blood cells (RBCs). Deformability is one of the key physiological and… Read More »Nonlinear Biomechanical Characteristics of Deep Deformation of Native RBC Membranes in Normal State and under Modifier Action