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World Science Day

Single pass Kelvin Force Microscopy

Sergei Magonov from NT-MDT captured this extremly impressing single pass Kelvin Force Micoscopy image of self-assemblies of semifluorinated alkanes (F12H12)

KPFM_01

Single-pass Kelvin Force Microscopy (KFM-PM) scan of self-assemblies of semifluorinated alkanes (F12H12) on HOPG. Height, capacitance gradients dC/dZ and dC/dV and surface potential. Images courtesy by Sergei Magonov, obtained with a NT-MDT Titanium scanning probe microscope and a NANOSENSORS PtSi-FM probe.

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Single molecule force spectroscopy with NANOSENSORS™ uniqprobe qp-CONT

High resolution imaging of the cytoplasmic side of bacteriorhodospin (BR) (left) and overlay of 6 force-distance curves (right) showing the controlled C-terminal unfolding of a single BR membrane protein from its native environment.

BR image & spectroscopy

The measurements were recorded in buffer solution with a FlexAFM V3 (Nanosurf) using a NANOSENSORS™ uniqprobe qp-CONT cantilever by Dr. Patrick Frederix from Nanosurf AG.

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Characterization of Interactions between Heparin/Glycosaminoglycan and Adeno-Associated Virus with NANOSENSORS™ Super Sharp Silicon AFM probes

Divergent effect of glycosaminoglycans on the in vitro aggregation of serum amyloid A (http://dx.doi.org/10.1016/j.biochi.2014.05.007). Characterization of Interactions between eparin/Glycosaminoglycan and Adeno-Associated Virus (http://dx.doi.org/10.1021/bi4008676)

Check out the excellent work by Javier Aguilera and his coauthors. The authors used NANOSENSORS™ Super Sharp Silicon AFM tips to demonstrate awesome morphological features of AAV-2 and complexes with different heparin oligosaccharides and investigated the effect of glycosaminoglycans (GAGs) on the aggregation of serum amyloid A (SAA).

2014-09-18 09_06_46-20140826-142157-Characterization of Interactions between Heparin_Glycosaminoglyc

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Application Note on Insulated Conductive Probes for combined AFM and Electrochemical studies (EC Probes)

Schematic of a wired and insulated NANOSENSORS Doped silicon ElectroChemical AFM Probe for combined AFM and ElectroChemical studies (EC-Probes).

In a new application note Ilya V. Popolov and Miklós Mohos from the University of Bern and Christoph Richter from NANOSENSORS show how insulated conductive probes can best be used for combined AFM and electrochemical studies.

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